Sclerotic Lesion
Most often, enchondromas are of no consequence and patients are asymptomatic. Enchondromas are benign cartilaginous neoplasms that are usually solitary lesions in intramedullary bone. The primary significant factors of enchondromas are related to their complications, most notably pathologic fracture, and a small incidence of malignant transformation. On basis on x-ray findings there are two differential diagnosis, one is enchondroma other is bone infarct. Following MRI confirmation follow up is recommended.
MRI findings may be useful in distinguishing enchondromas in the long bones from bone infarcts. Typically, bone infarcts are encapsulated by a serpiginous rind of decreased signal intensity on T1- and T2-weighted images. Frequently, this rind is subtended by a high-signal-intensity line. This finding has been called the double-line sign. Conversely, enchondromas tend to have lobulated borders with a cluster of numerous tiny locules of high-signal-intensity foci on T2-weighted images that appear to coalesce.
MRI findings may be useful in distinguishing enchondromas in the long bones from bone infarcts. Typically, bone infarcts are encapsulated by a serpiginous rind of decreased signal intensity on T1- and T2-weighted images. Frequently, this rind is subtended by a high-signal-intensity line. This finding has been called the double-line sign. Conversely, enchondromas tend to have lobulated borders with a cluster of numerous tiny locules of high-signal-intensity foci on T2-weighted images that appear to coalesce.
AbstractOsteolytic defects and osteoporosis are common in myeloma, while sclerotic lesions of bone are rare. Eighteen patients with increased bone density have been described in the literature and five patients are presented in this report. Diffuse increase in skeletal density, similar to that seen in the myelofibrosis-myelosclerosis syndrome, occurred in two patients, and progressive multiple focal areas of sclerosis with splenomegaly in a third. Two patients had solitary areas of sclerosis.
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The structure may be said to have undergone sclerotic changes or display sclerotic lesions, which refers to the process of sclerosis. Common medical conditions. According to the University of Washington, a sclerotic lesion of the bone usually results from a slow-growing bone disorder that allows the bone enough time to attempt the formation of a sclerotic area around the offender.
Although there was increased cortical and trabecular bone, osteoblastic activity was normal on histological sections. Whether the sclerosis was due to new bone formation or interference with bone resorptive processes could not be determined. Patients with polycythemia, myelofibrosis and myelosclerosis have been found to have, or later develop, myeloma. This has led to the suggestion that myeloma be included among the myeloproliferative disorders. At present the evidence for this interrelationship is the frequency of the association of these diseases.
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